No grain restriction
Rotation is on. That is the useful difference from the plywood calculator: the nest can turn a 400 × 800 side if it fills a leftover better.
Calculator
MDF cut list calculator
MDF has no face grain. Parts can rotate, which usually packs tighter than plywood with grain locked.
Parts
Edges
MDF edges need sealing or lipping if they will show. The optimiser does not add lipping strips — add them as extra parts if you cut them from the same sheet.
Worked example
Four tall 400 × 800 sides, two 1200 × 100 plinths and eight 80 × 400 packers. Rotation on, 3 mm kerf.
Questions
Is MDF the same as particle board?
No. Particle board (chipboard) is coarser and common for kitchen carcasses. Use the particle-board calculator if that is your stock.